SCHEMBL3842708

SCHEMBL3842708

COC(CCCNc1ccccc1)OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
ALDH1A1 P00352 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.41
KCNH3 Q9ULD8 3/20 0.40
HTR2A P28223 1/20 0.39
HRH1 P35367 1/20 0.39
PPARG P37231 1/20 0.39
GAA P10253 2/20 0.38
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38
KDM1A O60341 1/20 0.36
EHMT2 Q96KQ7 1/20 0.36
RCOR1 Q9UKL0 1/20 0.36
HDAC2 Q92769 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
BCHE P06276 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2255790 0.79 ALDH1A1 (0.64) MAPTALDH1A1L3MBTL1KCNH3HTR2A
SCHEMBL931749 0.76 MAPT (0.56) MAPTALDH1A1L3MBTL1GAAHTT
SCHEMBL3195231 0.76 MAPT (0.50) MAPTALDH1A1L3MBTL1KCNH3HTR2A
SCHEMBL1291694 0.76 MAPT (0.59) MAPTALDH1A1L3MBTL1HTR2AHRH1
SCHEMBL9572773 0.76 MAPT (0.59) MAPTALDH1A1L3MBTL1KCNH3HTR2A
SCHEMBL16234268 0.76 ALDH1A1 (0.59) MAPTALDH1A1L3MBTL1KCNH3HTR2A
SCHEMBL2915787 0.75 MAOA (0.58) MAPTGAAMEN1KMT2ABCHE
SCHEMBL1603895 0.75 MAPT (0.53) MAPTALDH1A1L3MBTL1KCNH3HTR2A
SCHEMBL4970157 0.75 ALDH1A1 (0.89) MAPTALDH1A1L3MBTL1KCNH3HDAC2
SCHEMBL2065279 0.75 ALDH1A1 (1.00) MAPTALDH1A1L3MBTL1KCNH3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1128214-B1 Photosensitive compound and photosensitive resin TOYO GOSEI KOGYO KK (JP) 2009-11-04 EP disclosed
US-6610791-B2 Substituted thiazole derivative; for use in color cathode ray tubes, display tubes, screen printing TOYO GOSAI KOGYO CO., LTD. (JP) 2003-08-26 US disclosed
US-20010047068-A1 Photosensitive compound and photosensitive resin TOYO GOSEI KOGYO CO., LTD. (JP) 2001-11-29 US disclosed
EP-1128214-A1 Photosensitive compound and photosensitive resin Toyo Gosei Kogyo Co., Ltd. (JP) 2001-08-29 EP disclosed