Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42559 | 0.98 | LMNA (0.53) | LMNAHSD11B1SLC6A3HDAC1ALDH1A1 | |
| SCHEMBL10002400 | 0.94 | LMNA (0.49) | LMNAHSD11B1SLC6A3HDAC1ALDH1A1 | |
| SCHEMBL379020 | 0.90 | HSD11B1 (0.49) | LMNAHSD11B1HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5794598 | 0.89 | HSD11B1 (0.48) | LMNAHSD11B1HDAC1ALDH1A1 | |
| SCHEMBL22027131 | 0.83 | LMNA (0.57) | LMNAHSD11B1ALDH1A1AKR1C1SMN1; SMN2 | |
| SCHEMBL1807150 | 0.83 | AKR1C1 (0.66) | LMNAHSD11B1SLC6A3HDAC1ALDH1A1 | |
| SCHEMBL29057707 | 0.83 | LMNA (0.57) | LMNAHSD11B1ALDH1A1AKR1C1SMN1; SMN2 | |
| SCHEMBL2701756 | 0.82 | ALOX5 (0.49) | LMNAHSD11B1HDAC1ALDH1A1 | |
| SCHEMBL29604970 | 0.81 | LMNA (0.55) | LMNAHSD11B1HDAC1ALDH1A1AKR1C1 | |
| SCHEMBL4992446 | 0.81 | LMNA (0.59) | LMNAHSD11B1ALDH1A1AKR1C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213255-A | Synthetic method of six-membered ring benzylamine compound | 上海泰坦科技股份有限公司 | 2022-03-22 | — | — | CN | disclosed |
| EP-2099754-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008073929-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |