Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847158 | 0.82 | KMT2A (0.39) | TSHRKMT2AMEN1PKMNPSR1 | |
| SCHEMBL3852701 | 0.77 | KMT2A (0.37) | TSHRKMT2AMEN1PKMNPSR1 | |
| SCHEMBL5253108 | 0.64 | TSHR (0.38) | TSHRKMT2AMEN1PKMNPSR1 | |
| SCHEMBL8390421 | 0.64 | TSHR (0.49) | TSHRKMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL4817660 | 0.63 | TSHR (0.43) | TSHRNPSR1MAPK1LMNAALDH1A1 | |
| SCHEMBL20129616 | 0.62 | KDM4E (0.56) | TSHRKMT2AMEN1PKMC5AR1 | |
| SCHEMBL20755413 | 0.62 | GAA (0.54) | TSHRKMT2AMEN1PKMKDM4E | |
| SCHEMBL5460658 | 0.61 | GAA (0.62) | TSHRKMT2AMEN1PKMKDM4E | |
| SCHEMBL14804540 | 0.61 | ALDH1A1 (0.58) | KMT2AMEN1NPSR1MAPK1LMNA | |
| SCHEMBL30941560 | 0.60 | NPC1 (0.36) | TSHRKMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |