Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847158 | 0.94 | KMT2A (0.39) | KMT2ATSHRMEN1PKMMAPT | |
| SCHEMBL3842877 | 0.77 | TSHR (0.38) | KMT2ATSHRMEN1PKMMAPT | |
| SCHEMBL3843013 | 0.73 | PDE2A (0.43) | KMT2APDE2AMEN1PDE10AMAPT | |
| SCHEMBL5779311 | 0.72 | TRPV1 (0.35) | KMT2ATSHRPDE2AMEN1PKM | |
| SCHEMBL27543784 | 0.71 | TRPV1 (0.39) | KMT2ATSHRMEN1PKMMAPT | |
| SCHEMBL27543783 | 0.71 | TSHR (0.43) | KMT2ATSHRMEN1PKMMAPT | |
| SCHEMBL4818506 | 0.71 | TSHR (0.46) | KMT2ATSHRPDE2AMEN1MAPT | |
| SCHEMBL5251841 | 0.71 | PTPN11 (0.36) | TSHRPDE2APDE10AMAPTTRPV1 | |
| SCHEMBL3861650 | 0.71 | PDE2A (0.41) | KMT2APDE2AMEN1PDE10AMAPT | |
| SCHEMBL344327 | 0.70 | TSHR (0.46) | KMT2ATSHRPDE2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |