Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848685 | 0.96 | AGTR1 (0.49) | AGTR2AGTR1 | |
| SCHEMBL3849928 | 0.92 | AGTR1 (0.49) | AGTR2AGTR1PPARGKCNH2 | |
| SCHEMBL7438005 | 0.92 | AGTR1 (0.52) | AGTR2AGTR1 | |
| SCHEMBL7889722 | 0.91 | AGTR1 (0.43) | AGTR2AGTR1 | |
| SCHEMBL668712 | 0.89 | AGTR1 (0.54) | AGTR2AGTR1 | |
| SCHEMBL668713 | 0.88 | AGTR1 (0.49) | AGTR2AGTR1PPARG | |
| SCHEMBL3842278 | 0.88 | AGTR1 (0.44) | AGTR2AGTR1 | |
| SCHEMBL7428535 | 0.87 | AGTR1 (0.46) | AGTR2AGTR1 | |
| SCHEMBL7300844 | 0.86 | AGTR1 (0.51) | AGTR2AGTR1 | |
| SCHEMBL7886577 | 0.86 | AGTR1 (0.40) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884240-B1 | PHARMACEUTICAL FOR PREVENTION OR TREATMENT OF BONE METABOLIC DISEASE | DAIICHI SANKYO CO LTD (JP) | 2009-11-11 | — | — | EP | claimed |