SCHEMBL7438005

SCHEMBL7438005

CCCCc1nc(C(=O)OCOC(=O)C(C)(C)C)c(C(C)(C)O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.52
AGTR2 P50052 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7428535 0.95 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL3842922 0.92 AGTR2 (0.55) AGTR1AGTR2
SCHEMBL3849928 0.90 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL7910761 0.89 AGTR1 (0.50) AGTR1AGTR2
SCHEMBL667461 0.89 AGTR1 (0.53) AGTR1AGTR2
SCHEMBL667462 0.88 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL12991354 0.87 AGTR2 (0.56) AGTR1AGTR2
SCHEMBL7910716 0.87 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL3848685 0.87 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL7300844 0.87 AGTR1 (0.51) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503785-B1 1-Biphenylimidazole derivatives, their preparation and their therapeutic use SANKYO CO (JP) 2001-04-25 EP claimed