Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846790 | 0.87 | KMT2A (0.33) | KCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL2865982 | 0.79 | MEN1 (0.41) | PTGS2MAPTPTGS1GAAABCB11 | |
| SCHEMBL26406461 | 0.75 | TAAR1 (0.42) | PTGS2KCNH2MAPTPTGS1GAA | |
| SCHEMBL3848780 | 0.75 | RAPGEF4 (0.34) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9228613 | 0.72 | KCNH2 (0.46) | PTGS2KCNH2PTGS1GAAABCB11 | |
| SCHEMBL3845491 | 0.72 | TRPM5 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL22322672 | 0.71 | GAA (0.39) | PTGS2KCNH2MAPTPTGS1GAA | |
| SCHEMBL5216623 | 0.69 | TAAR1 (0.45) | PTGS2KCNH2MAPTPTGS1GAA | |
| SCHEMBL29565775 | 0.69 | TAAR1 (0.45) | PTGS2KCNH2MAPTPTGS1GAA | |
| SCHEMBL14824903 | 0.69 | GAA (0.49) | PTGS2KCNH2PTGS1GAAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |