Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3850999 | 0.87 | RAPGEF4 (0.39) | RAPGEF4HPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3845491 | 0.79 | TRPM5 (0.33) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL3842935 | 0.75 | PTGS2 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24072557 | 0.72 | RAPGEF4 (0.41) | RAPGEF4JAK2 | |
| SCHEMBL3846790 | 0.67 | KMT2A (0.33) | ALDH1A1 | |
| SCHEMBL6036163 | 0.66 | SMN1; SMN2 (0.41) | HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3848778 | 0.64 | — | — | |
| SCHEMBL11421022 | 0.64 | MEN1 (0.47) | JAK2HTTSMN1; SMN2 | |
| SCHEMBL3091816 | 0.63 | RAPGEF4 (0.43) | RAPGEF4 | |
| SCHEMBL6036726 | 0.63 | RAPGEF4 (0.49) | RAPGEF4HPGDHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |