SCHEMBL3843022

SCHEMBL3843022

CC(C)(C)NCc1ccccc1C1c2ccccc2-c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
ATM Q13315 1/20 0.38
HTR2A P28223 1/20 0.37
PDCD1LG2 Q9BQ51 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
ADRB1 P08588 4/20 0.35
ADRB2 P07550 2/20 0.35
PKM P14618 1/20 0.35
DHFR P00374 1/20 0.35
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
LMNA P02545 1/20 0.34
RAD52 P43351 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22548784 0.77 KDM4E (0.49) HTTALDH1A1KDM4EHPGDMEN1
SCHEMBL3192818 0.76 HTT (0.37) HTTALDH1A1KDM4EHPGDMEN1
SCHEMBL3215722 0.74 KMT2A (0.41) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL3845070 0.74 HIF1A (0.41) ALDH1A1MEN1KMT2APOLBATM
SCHEMBL10455243 0.74 HTR2A (0.45) MEN1KMT2APOLBATMHTR2A
SCHEMBL15961523 0.73 DPP4 (0.48) HTTALDH1A1KDM4EHPGDKMT2A
SCHEMBL3204622 0.72 SIGMAR1 (0.36) HTTALDH1A1KDM4EHPGDMEN1
SCHEMBL3202576 0.72 BCHE (0.53) KDM4EBCHEACHECYP2D6CHRM1
SCHEMBL21800025 0.72 HTT (0.43) HTTALDH1A1KDM4EHPGDMEN1
SCHEMBL13958900 0.72 HTT (0.43) HTTALDH1A1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed