Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803990 | 0.83 | TP53 (0.47) | CYP2D6MEN1KMT2A | |
| SCHEMBL27558719 | 0.80 | HTR2A (0.52) | HTR2AACHEGPR3CA1CA2 | |
| SCHEMBL29175309 | 0.78 | HTR2A (0.45) | HTR2AGPR3CA1CA2POLB | |
| SCHEMBL8655669 | 0.77 | HTR2A (0.37) | HTR2AACHEGPR3BCHECA1 | |
| SCHEMBL28504288 | 0.77 | HTR2A (0.43) | HTR2AACHEGPR3CA1CA2 | |
| SCHEMBL28502205 | 0.77 | HTR2A (0.43) | HTR2AACHEGPR3BCHECA1 | |
| SCHEMBL28946011 | 0.75 | CYP1A2 (0.39) | HTR2AHTR1AMEN1KMT2AATM | |
| SCHEMBL7646509 | 0.75 | GABRA1 (0.45) | HTR2AACHEGPR3BCHECA1 | |
| SCHEMBL3202576 | 0.74 | BCHE (0.53) | ACHEBCHECA2CYP2D6CHRM2 | |
| SCHEMBL3843022 | 0.74 | HTT (0.38) | HTR2AACHEGPR3BCHECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387690-A1 | Process for preparing a syndiotactic polyolefin | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-19 | — | — | EP | disclosed |