Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ODC1 | P11926 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859617 | 0.78 | MAOB (0.59) | MAOBALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL29959798 | 0.78 | MAOB (0.59) | MAOBALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL17237767 | 0.73 | ABCB1 (0.53) | ALDH1A1KMT2AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL5804679 | 0.73 | HDAC4 (0.76) | HDAC4HDAC2HDAC8ALDH1A1KMT2A | |
| SCHEMBL16812107 | 0.71 | HDAC4 (0.73) | HDAC4HDAC2HDAC8ALDH1A1KMT2A | |
| SCHEMBL642228 | 0.70 | HDAC4 (0.58) | HDAC4HDAC2HDAC8ALDH1A1LMNA | |
| SCHEMBL6255493 | 0.69 | MAOB (0.40) | MAOBALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL1764660 | 0.69 | KDM4E (0.56) | ALDH1A1KMT2AMEN1ODC1MAOA | |
| Pisonin A SCHEMBL30895182 | 0.66 | PTGS1 (0.61) | KDM4EMAPTPOLB | |
| SCHEMBL29568413 | 0.66 | MAOB (0.48) | MAOBALDH1A1LMNAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2087350-A1 | COMPOUNDS | The Robert Gordon University (GB) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008062184-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY (GB) | 2008-05-29 | — | — | WO | disclosed |
| EP-1534698-A1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | The Rowett Research Institute (GB) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004007475-A1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RESEARCH INSTITUTE (GB) | 2004-01-22 | — | — | WO | disclosed |