Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.45 |
| ▸ | TUBB | P07437 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718718 | 0.88 | KDM4E (0.54) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL774316 | 0.83 | KDM4E (0.75) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL380907 | 0.81 | ADORA3 (0.73) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL5135083 | 0.79 | ABCG2 (0.65) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL1765291 | 0.78 | KDM4E (0.84) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL775093 | 0.78 | MGAM (0.53) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL17237780 | 0.76 | MAOA (0.59) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL775094 | 0.75 | ABCG2 (0.60) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL25065758 | 0.75 | MEN1 (0.70) | KDM4EHSD17B10ABCG2ABCB1MEN1 | |
| SCHEMBL1765292 | 0.74 | ADORA3 (0.67) | KDM4ECYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118091005-A | Method for detecting multiple components in deer astragalus kidney-tonifying particles | 上海市第七人民医院(上海中医药大学附属第七人民医院) | 2024-05-28 | — | — | CN | claimed |
| CN-115736151-A | Method for preparing beverage from citrus processing by-product | 北冰洋（北京）饮料食品有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-110496163-A | The preparation method of citrous bud or flower or branch or leaf or fruit active component or ingredient and its application in medicine preparation | UNIV JIANGXI TRADITIONAL CHINESE MEDICINE | 2019-11-26 | — | — | CN | claimed |
| CN-110038054-A | Active component improves sleep or antidepression or improves in failure of memory drug or food and applies in preparation in gardenia and branches and leaves fruit | 江西中医药大学 | 2019-07-23 | — | — | CN | claimed |
| US-8945646-B2 | Method for manufacturing polymethoxyflavones that are highly stable over time and have reduced residual pesticide levels | OGAWA & CO., LTD. (JP) | 2015-02-03 | — | — | US | claimed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | claimed |
| EP-2530080-A1 | METHOD FOR MANUFACTURING POLYMETHOXYFLAVONES THAT ARE HIGHLY STABLE OVER TIME AND HAVE REDUCED RESIDUAL PESTICIDE LEVELS | Ogawa & Co., Ltd. (JP) | 2012-12-05 | — | — | EP | claimed |
| US-20120301596-A1 | METHOD FOR MANUFACTURING POLYMETHOXYFLAVONES THAT ARE HIGHLY STABLE OVER TIME AND HAVE REDUCED RESIDUAL PESTICIDE LEVELS | OGAWA & CO LTD (JP) | 2012-11-29 | — | — | US | claimed |
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | DEEPSENSE BIOTECHNOLOGIES INC (US) | 2026-04-30 | — | — | US | disclosed |
| CN-120009445-A | Detection method and kit for ageing process | 中国检验检疫科学研究院 | 2025-05-16 | — | — | CN | disclosed |
| US-12195436-B2 | Method for decomposing flavonoid glycoside and method for producing flavonoid | RESONAC CORPORATION (JP) | 2025-01-14 | — | — | US | disclosed |
| US-11884641-B2 | Method for decomposing flavonoid glycoside and method for producing flavonoid | RESONAC CORPORATION (JP) | 2024-01-30 | — | — | US | disclosed |
| CN-115736151-A | Method for preparing beverage from citrus processing by-product | 北冰洋（北京）饮料食品有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-114796425-A | Waist support patch and preparation method thereof | 周维兰 | 2022-07-29 | — | — | CN | disclosed |
| WO-2007024982-A2 | METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION | WELLGEN, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-02-22 | — | — | US | disclosed |
| WO-2006127996-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-11-30 | — | — | WO | disclosed |
| US-6987125-B1 | Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2006-01-17 | — | — | US | disclosed |
| US-20050226828-A1 | Method for whitening human skin | NOF CORPORATION | 2005-10-13 | — | — | US | disclosed |
| WO-2002053152-A1 | COMPOSITION CONTAINING FLAVONOIDS FOR TREATMENT BRAIN DISORDERS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDICINE (GB) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | GYS1, PYGM, PRDX5 | KDM4E 121/4885CYP3A4 144/4885CYP2C9 93/4885 |
| US-20050226828-A1 | Method for whitening human skin | CUTA, POLN, PLIN5 | KDM4E 454/4885CYP3A4 2403/4885CYP2C9 1637/4885 |
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | PLIN3, PNLIP, FABP2 | KDM4E 2460/4885CYP3A4 39/4885CYP2C9 178/4885 |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | PLIN5, FANCF, COXFA4 | KDM4E 1277/4885CYP3A4 390/4885CYP2C9 387/4885 |
| US-20120301596-A1 | METHOD FOR MANUFACTURING POLYMETHOXYFLAVONES THAT ARE HIGHLY STABLE OVER TIME AND HAVE REDUCED RESIDUAL PESTICIDE LEVELS | VGF, DDT, F2 | KDM4E 46/4885CYP3A4 65/4885CYP2C9 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.