Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321412 | 0.90 | CPB2 (0.49) | CPB2CPB1ALDH1A1GFER | |
| SCHEMBL10609690 | 0.82 | TDP1 (0.41) | ATMTDP1ALDH1A1GFER | |
| SCHEMBL13617409 | 0.82 | TDP1 (0.41) | ATMTDP1ALDH1A1GFER | |
| SCHEMBL12329476 | 0.80 | SCN9A (0.47) | SCN9ASIRT2CPB2CPB1 | |
| SCHEMBL2084230 | 0.80 | ALDH1A1 (0.48) | TDP1ALDH1A1GFER | |
| SCHEMBL3428546 | 0.78 | ITGB3 (0.47) | CPB2CPB1 | |
| SCHEMBL3009904 | 0.78 | ITGB3 (0.47) | CPB2CPB1 | |
| SCHEMBL3009900 | 0.78 | ITGB3 (0.47) | CPB2CPB1 | |
| SCHEMBL12199027 | 0.77 | SCN9A (0.46) | SCN9ASIRT2CPB2CPB1TDP1 | |
| SCHEMBL25836690 | 0.77 | KDM4E (0.46) | ATMTDP1ALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311488-B1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | PFIZER LTD (GB) | 2009-11-04 | — | — | EP | disclosed |