Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793193 | 0.98 | ALDH1A1 (0.52) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| Hydrochloric Acid SCHEMBL28325576 | 0.98 | ALDH1A1 (0.52) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| Quinoline SCHEMBL28240764 | 0.95 | ALDH1A1 (0.59) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| Isoquinoline SCHEMBL28860064 | 0.86 | CYP11B2 (0.47) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL31588535 | 0.85 | POLB (0.57) | ALDH1A1MEN1CASP1KMT2AHTT | |
| SCHEMBL29843637 | 0.85 | POLB (0.57) | ALDH1A1MEN1CASP1KMT2AHTT | |
| SCHEMBL506632 | 0.85 | POLB (0.57) | ALDH1A1MEN1CASP1KMT2AHTT | |
| Quinoline SCHEMBL28269682 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MEN1CASP1KMT2AHTT | |
| Fluoride SCHEMBL28218511 | 0.83 | POLB (0.55) | ALDH1A1MEN1CASP1KMT2AHTT | |
| SCHEMBL28153180 | 0.83 | POLB (0.55) | ALDH1A1MEN1CASP1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382475-A | NRF2 activator | 比奥根MA公司 | 2019-10-25 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| CN-105025899-B | Having a2AHeterobicyclically substituted- [1,2,4 ] antagonists]Triazolo [1,5-c]Quinazoline-5-amine compounds | 默沙东公司 | 2017-08-18 | — | — | CN | claimed |
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | claimed |
| CN-106458994-A | Biaryl kinase inhibitors | 百时美施贵宝公司 | 2017-02-22 | — | — | CN | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| CN-104837490-A | Pyrimido [4,5-b ] quinoline-4, 5(3H,10H) -diones as nonsense mutation suppressors | NOVARTIS AG | 2015-08-12 | — | — | CN | claimed |
| EP-2699572-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Origenis GmbH (DE) | 2014-02-26 | — | — | EP | claimed |
| WO-2012143143-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | claimed |
| CN-1934116-B | Tricyclic benzopyran compounds useful as antiarrhythmic agents | NISSAN CHEMICAL IND LTD | 2012-10-10 | — | — | CN | claimed |
| CN-101429200-A | Tricyclic benzopyran compound as anti-arrhythmic agents | NISSAN CHEMICAL IND LTD (JP) | 2009-05-13 | — | — | CN | claimed |
| CN-100432055-C | Tricyclic protein kinase inhibitors | WYETH CORP (US) | 2008-11-12 | — | — | CN | claimed |
| CN-1934116-A | Tricyclic benzopyran compounds useful as antiarrhythmic agents | NISSAN CHEMICAL IND LTD (JP) | 2007-03-21 | — | — | CN | claimed |
| CN-1704404-A | Tricyclic protein kinase inhibitors | WYETH CORP (US) | 2005-12-07 | — | — | CN | claimed |
| CN-1121391-C | Substituted 3-cyano quinolines | AMERICAN CYANAMID CO (US) | 2003-09-17 | — | — | CN | claimed |
| CN-1437584-A | Tricyclic protein kinase inhibitors | WYETH CORP (US) | 2003-08-20 | — | — | CN | claimed |
| CN-1429126-A | Use of cyanoquinolines for treating or inhibiting colonic polyps | AMERICAN CYANAMID CO (US) | 2003-07-09 | — | — | CN | claimed |
| EP-1242382-A1 | TRICYCLIC PROTEIN KINASE INHIBITORS | Wyeth (US) | 2002-09-25 | — | — | EP | claimed |
| WO-2001047892-A1 | TRICYCLIC PROTEIN KINASE INHIBITORS | WYETH (US) | 2001-07-05 | — | — | WO | claimed |
| CN-1259125-A | Substituted 3-cyanoquinolines | AMERICAN CYANAMID CO (US) | 2000-07-05 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | ALDH1A1 4757/4885MEN1 722/4885CASP1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.