SCHEMBL3843676

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3845116	0.84	HTR7 (0.51)	SIGMAR1HTR7KMT2AHTR1ADRD2
	SCHEMBL14347032	0.83	HTR1D (0.41)	HTR1DSIGMAR1HTR7
	SCHEMBL3849003	0.82	HTR7 (0.42)	HTR1DSIGMAR1HTR7HTR1ADRD2
	SCHEMBL3850857	0.81	JAK1 (0.38)	HTR1DSIGMAR1HTR7KMT2A
	SCHEMBL3848083	0.80	SIGMAR1 (0.55)	SIGMAR1KMT2AHTR1ADRD2PPARG
	SCHEMBL3847417	0.78	DRD2 (0.41)	HTR1DSIGMAR1HTR1ADRD2DRD4
	SCHEMBL13630507	0.78	DRD2 (0.45)	DRD2
	SCHEMBL4493641	0.78	DRD2 (0.45)	DRD2
	SCHEMBL4493623	0.78	SIGMAR1 (0.55)	SIGMAR1HTR1ADRD2PPARGPPARA
	SCHEMBL4485693	0.78	DRD2 (0.54)	SIGMAR1HTR1ADRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.