Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843847 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CES2CES1APPELANE | |
| SCHEMBL27955446 | 0.82 | CES2 (0.52) | ALDH1A1CES2CES1APPSMN1; SMN2 | |
| SCHEMBL3843448 | 0.76 | APP (0.45) | ALDH1A1CES2CES1APPMAPT | |
| SCHEMBL170296 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CES2CES1APPL3MBTL1 | |
| SCHEMBL3846147 | 0.74 | CES2 (0.44) | ALDH1A1CES2CES1ELANEL3MBTL1 | |
| SCHEMBL9194201 | 0.74 | CES2 (0.44) | ALDH1A1CES2CES1ELANEL3MBTL1 | |
| SCHEMBL28126867 | 0.74 | CES2 (0.44) | ALDH1A1CES2CES1ELANEL3MBTL1 | |
| SCHEMBL701017 | 0.74 | CES2 (0.44) | ALDH1A1CES2CES1ELANEL3MBTL1 | |
| SCHEMBL2458795 | 0.72 | CES2 (0.42) | ALDH1A1CES2CES1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5828005 | 0.72 | CES1 (0.48) | ALDH1A1CES2CES1ELANEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318610-A1 | ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES | SUMITOMO BAKELITE CO., LTD (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2117009-A1 | ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Co., Ltd. (JP) | 2009-11-11 | — | — | EP | disclosed |