SCHEMBL170296

SCHEMBL170296

[C](=C(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
APP P05067 1/20 0.43
CES1 P23141 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
CYP3A4 P08684 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 3/20 0.39
CES2 O00748 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
SRD5A2 P31213 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082825 0.84 VCP (0.35) ALDH1A1APPCES1MAPTMEN1
SCHEMBL451153 0.74 APP (0.39) ALDH1A1APPCES1TDP1CYP3A4
SCHEMBL3843845 0.74 ALDH1A1 (0.42) ALDH1A1APPCES1TDP1MAPT
SCHEMBL3843847 0.74 ALDH1A1 (0.42) ALDH1A1APPCES1TDP1MAPT
SCHEMBL7136968 0.73 CES1 (0.45) ALDH1A1CES1TDP1CYP3A4MAPT
SCHEMBL2181511 0.73 ALDH1A1 (0.53) ALDH1A1CES1TDP1CYP3A4MAPT
SCHEMBL8152963 0.70 ALDH1A1 (0.39) ALDH1A1APPCES1TDP1CYP3A4
SCHEMBL6509808 0.70 CES1 (0.46) ALDH1A1APPCES1TDP1MEN1
SCHEMBL1421154 0.69 AKT1 (0.45) ALDH1A1APPCES1TDP1MAPT
SCHEMBL4916640 0.69 AKT1 (0.45) ALDH1A1APPCES1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2274 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024401-B Triphenylvinyl thiophene compound and preparation method and application thereof 中国矿业大学 2024-01-26 CN claimed
CN-117024401-A Triphenylvinyl thiophene compound and preparation method and application thereof 中国矿业大学 2023-11-10 CN claimed
CN-115745875-A Light-operated organic electroluminescent material containing triphenylethylene group, and synthesis method and application thereof 西北工业大学宁波研究院 2023-03-07 CN claimed
CN-115028810-A Triphenylamine-tetra/triphenylethylene conjugated porous polymer nano particle and preparation method thereof 长春理工大学 2022-09-09 CN claimed
CN-114751824-A Preparation method and application of conjugate material containing ethyl benzoate structure 南京信息工程大学 2022-07-15 CN claimed
EP-2711413-B2 Washing agent and method for metering a washing agent MIELE & CIE (DE) 2022-04-13 EP claimed
CN-113980041-A Preparation and application of star-type non-fullerene solar cell receptor 南京林业大学 2022-01-28 CN claimed
CN-110642852-B Organic AIE photosensitive probe with mitochondrion targeting function and preparation method and application thereof 南开大学 2020-10-27 CN claimed
CN-110642852-A Organic AIE photosensitive probe with mitochondrion targeting function and preparation method and application thereof 南开大学 2020-01-03 CN claimed
EP-2711413-B1 Washing agent and method for metering a washing agent MIELE & CIE (DE) 2018-11-28 EP claimed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US claimed
CN-1264386-A Alkene borates and process for covalently coupling organic compounds COMMW SCIENT IND RES ORG (AU) 2000-08-23 CN claimed
US-4940469-A Low-foaming composition for finishing synthetic fibres: dye or optical brightener or ultra-violet absorber and alkylene-diamide:ethylene-distearamide CIBA-GEIGY CORPORATION (US) 1990-07-10 US claimed
EP-0055562-B1 CEPHALOSPORIN DERIVATIVES ICI PHARMA (FR) 1986-02-12 EP claimed
EP-0055099-B1 PENICILLIN DERIVATIVES ICI PHARMA (FR) 1984-10-24 EP claimed
EP-0075434-A2 Cephalosporins, their preparation and their pharmaceutical compositions ICI PHARMA (FR) 1983-03-30 EP claimed
EP-0072608-A2 Process for the preparation of cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-02-23 EP claimed
EP-0071370-A2 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them ICI PHARMA (FR) 1983-02-09 EP claimed
EP-0055562-A2 Cephalosporin derivatives ICI PHARMA (FR) 1982-07-07 EP claimed
EP-0055099-A1 Penicillin derivatives ICI PHARMA (FR) 1982-06-30 EP claimed