Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561916 | 0.92 | RAD52 (0.33) | LMNAKMT2ARAD52 | |
| SCHEMBL2557071 | 0.91 | RAD52 (0.33) | LMNAKMT2ARAD52 | |
| SCHEMBL9551034 | 0.85 | LMNA (0.36) | LMNAKMT2A | |
| SCHEMBL10824457 | 0.85 | KMT2A (0.33) | LMNAKMT2A | |
| SCHEMBL10443872 | 0.83 | LMNA (0.37) | LMNAKMT2A | |
| SCHEMBL9176002 | 0.83 | BRD4 (0.36) | LMNA | |
| SCHEMBL11857121 | 0.83 | LMNA (0.34) | LMNAKMT2A | |
| SCHEMBL5292581 | 0.82 | LMNA (0.36) | LMNAKMT2A | |
| SCHEMBL8412914 | 0.81 | LMNA (0.35) | LMNAKMT2A | |
| SCHEMBL18478875 | 0.81 | RAD52 (0.33) | LMNARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2115499-B1 | METHOD FOR IMPARTING HYDROGEL CONTACT LENSES WITH DESIRED PROPERTIES | NOVARTIS AG (CH) | 2015-11-11 | — | — | EP | disclosed |
| EP-2115499-A2 | METHOD FOR IMPARTING HYDROGEL CONTACT LENSES WITH DESIRED PROPERTIES | Novartis Ag (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2009055082-A2 | METHOD FOR IMPARTING HYDROGEL CONTACT LENSES WITH DESIRED PROPERTIES | NOVARTIS AG (CH) | 2009-04-30 | — | — | WO | disclosed |