SCHEMBL8412914

SCHEMBL8412914

C=C(CCCO)C(=O)O.C=CN1CCCC1=O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.33
TBXAS1 P24557 2/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10443872 0.92 LMNA (0.37) LMNAKMT2ATSHR
SCHEMBL11857121 0.88 LMNA (0.34) LMNAKMT2A
SCHEMBL9551034 0.84 LMNA (0.36) LMNAKMT2ATSHR
SCHEMBL1561916 0.84 RAD52 (0.33) LMNAKMT2A
SCHEMBL2557071 0.83 RAD52 (0.33) LMNAKMT2A
SCHEMBL8603667 0.83 KMT2A (0.34) LMNAKMT2A
Itaconate SCHEMBL17687381 0.81 ALOX15 (0.47) LMNAKMT2ATSHR
SCHEMBL5292581 0.81 LMNA (0.36) LMNAKMT2ATSHR
SCHEMBL3843897 0.81 LMNA (0.33) LMNAKMT2A
SCHEMBL17503450 0.80 SMN1; SMN2 (0.46) LMNAKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0627476-B1 PHOTOPOLYMERIZATION INITIATOR COMPOSITION FOR VISIBLE RAY POLYMERIZABLE ADHESIVE ADELL CO LTD (JP) 1999-08-04 EP disclosed
US-5607985-A BENZOYL PHOSPHINE OXIDE, CAMPHORQUINONE ADELL CO., LTD. (JP) 1997-03-04 US disclosed
EP-0627476-A1 PHOTOPOLYMERIZATION INITIATOR COMPOSITION FOR VISIBLE RAY POLYMERIZABLE ADHESIVE ADELL CO., LTD. (JP) 1994-12-07 EP disclosed
US-4925773-A PHOTOCURABLE RESIN KABUSHIKI KAISHA TOSHIBA (JP) 1990-05-15 US disclosed