SCHEMBL38440

SCHEMBL38440

C1=Nc2sccc2[N]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2925217 0.56
SCHEMBL9684723 0.56
SCHEMBL450432 0.55
SCHEMBL6657093 0.54
SCHEMBL959790 0.52
SCHEMBL871620 0.50
SCHEMBL10066089 0.27
SCHEMBL3000562 0.26
Water SCHEMBL28239689 0.26
SCHEMBL6640735 0.26

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 561 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024094170-A1 INHIBITOR OF UBIQUITIN-SPECIFIC PROTEASE 1 AND USE THEREOF 深圳晶泰科技有限公司 2024-05-10 WO claimed
CN-111205310-A Heterocyclic fused pyrimidine derivative, and pharmaceutical composition and application thereof 上海迪诺医药科技有限公司 2020-05-29 CN claimed
CN-101312966-A Benzothiazole cyclobutyl amine derivatives and their use as histamine-3 receptors ligands ABBOTT LAB (US) 2008-11-26 CN claimed
JP-2002506073-A 2002-02-26 JP claimed
US-20020019412-A1 MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) NOVO NORDISK A/S (DK) 2002-02-14 US claimed
EP-1062218-A1 MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) NOVO NORDISK A/S (DK) 2000-12-27 EP claimed
WO-1999046268-A1 MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) NOVO NORDISK A/S (DK) 1999-09-16 WO claimed
US-20240238460-A1 IMPROVED PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETING RADIOPHARMACEUTICALS AND USES THEREOF TELIX PHARMACEUTICALS INNOVATIONS PTY LTD (AU) 2024-07-18 US disclosed
EP-4398940-A1 ACETYLATED SIALIC ACID GLYCOCLUSTERS AND THEIR USES FOR TREATING INFECTIOUS DISEASES Université catholique de Louvain (BE) 2024-07-17 EP disclosed
EP-4399178-A1 PROCESS FOR THE PRODUCTION OF HYDROGEN THROUGH ELECTRIFICATION OF WATER GAS SHIFT REACTION TotalEnergies OneTech (FR) 2024-07-17 EP disclosed
WO-2024146923-A1 TUBULIN POLYMERIZATION INHIBITORS AB SCIENCE (FR) 2024-07-11 WO disclosed
US-12030866-B2 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD SPRINGWORKS THERAPEUTICS, INC. (US) 2024-07-09 US disclosed
WO-2024140687-A1 S1PR2 REGULATOR AND USE THEREOF 北京昌平实验室 2024-07-04 WO disclosed
CN-1300279-A Modulators of protein tyrosine phosphatases NOVO NORDISK AS (DK) 2001-06-20 CN disclosed
EP-1062218-A1 MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) NOVO NORDISK A/S (DK) 2000-12-27 EP disclosed
CN-1268942-A Sulfonamide compounds and medicinal use thereof FUJISAWA PHARMACEUTICAL CO (JP) 2000-10-04 CN disclosed
EP-0995742-A1 SULFONAMIDE COMPOUNDS AND MEDICINAL USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-04-26 EP disclosed
WO-1999046268-A1 MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) NOVO NORDISK A/S (DK) 1999-09-16 WO disclosed
US-5215983-A Useful for treatment of infectious diseases in a human as well as animal FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-06-01 US disclosed
EP-0424832-A2 Carbapenem compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-05-02 EP disclosed