Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | MC4R | P32245 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22059169 | 0.81 | SIGMAR1 (0.64) | SIGMAR1MC4RCCR3KMT2AHTR7 | |
| SCHEMBL10501364 | 0.81 | KCNH2 (0.57) | SIGMAR1HTR7KCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL8821971 | 0.80 | SIGMAR1 (0.62) | SIGMAR1MC4RCCR3KMT2AHTR7 | |
| SCHEMBL24148078 | 0.79 | ACHE (0.62) | CCR3 | |
| SCHEMBL3844018 | 0.79 | SIGMAR1 (0.60) | SIGMAR1MC4RCCR3KMT2AHTR7 | |
| SCHEMBL27803123 | 0.79 | CCR3 (0.63) | SIGMAR1MC4RCCR3HTR7 | |
| SCHEMBL6659339 | 0.78 | SIGMAR1 (0.86) | SIGMAR1MC4RCCR3KMT2A | |
| SCHEMBL14431493 | 0.78 | — | — | |
| SCHEMBL6957735 | 0.78 | MC4R (0.65) | SIGMAR1MC4RCCR3 | |
| SCHEMBL12916046 | 0.77 | SIGMAR1 (0.64) | SIGMAR1KMT2AHTR7HTR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979354-B1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | EP | disclosed |