Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.75 |
| ▸ | RAB9A | P51151 | 6/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475206 | 0.86 | SMN1; SMN2 (0.77) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL1574466 | 0.86 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL2069278 | 0.86 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL8341784 | 0.84 | SMN1; SMN2 (0.75) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL8339292 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL14800165 | 0.81 | GAA (1.00) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL18550718 | 0.81 | MAPT (1.00) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL2885708 | 0.80 | TRPM8 (0.78) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL8345831 | 0.80 | RAB9A (0.86) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL31301505 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9ANPC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979354-B1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | EP | disclosed |