Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.86 |
| ▸ | NPC1 | O15118 | 4/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.86 |
| ▸ | POLB | P06746 | 1/20 | 0.86 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2069278 | 0.93 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL289554 | 0.87 | SMN1; SMN2 (0.85) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL8343603 | 0.85 | SMN1; SMN2 (0.64) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL12475206 | 0.81 | SMN1; SMN2 (0.77) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL1574466 | 0.81 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL892234 | 0.81 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL8868337 | 0.80 | RAB9A (0.74) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL8866993 | 0.80 | XDH (1.00) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL8341784 | 0.80 | SMN1; SMN2 (0.75) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL3844047 | 0.80 | SMN1; SMN2 (0.75) | RAB9ASMN1; SMN2NPC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |