Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586239 | 0.80 | PTGS2 (0.48) | PTGS2L3MBTL1TNKSTNKS2ALDH1A1 | |
| SCHEMBL24696666 | 0.75 | PTGS2 (0.42) | PTGS2L3MBTL1BRD4TNKSTNKS2 | |
| SCHEMBL6965670 | 0.74 | CCNT1 (0.45) | PTGS2L3MBTL1BRD4TNKSTNKS2 | |
| SCHEMBL678904 | 0.72 | L3MBTL1 (0.51) | PTGS2L3MBTL1BRD4PTPRCPTPN1 | |
| SCHEMBL14704902 | 0.70 | HTR7 (0.49) | PTGS2MAPT | |
| SCHEMBL8959838 | 0.68 | HTR2A (0.62) | PTGS2APP | |
| SCHEMBL2570271 | 0.67 | CCNT1 (0.44) | — | |
| SCHEMBL23273627 | 0.66 | CA1 (0.50) | PTGS2BRD4ALDH1A1KDM4EAPP | |
| SCHEMBL29429633 | 0.66 | CA1 (0.71) | L3MBTL1ALDH1A1KDM4EMAPTAPP | |
| SCHEMBL301996 | 0.66 | CA1 (0.71) | L3MBTL1ALDH1A1KDM4EMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048126-A1 | Benzocycloheptane derivatives as selectively active oestrogens | Bayer Schering Pharma AG (DE) | 2009-04-15 | — | — | EP | disclosed |