SCHEMBL3844232

SCHEMBL3844232

N#Cc1ccc(SCCC(=O)O)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.48
MAOA P21397 5/20 0.47
MAOB P27338 5/20 0.47
SLC22A12 Q96S37 1/20 0.43
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
GLA P06280 1/20 0.42
CYP3A4 P08684 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
AR P10275 3/20 0.40
TRPV4 Q9HBA0 1/20 0.40
KMO O15229 1/20 0.40
TP53 P04637 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
S1PR3 Q99500 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1014938 0.81 DAO (0.49) DAOMAOAMAOBKDM4ECYP1A2
SCHEMBL11068279 0.81 HTT (0.53) DAOCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL10050946 0.79 MAOB (0.56) MAOAMAOBSLC22A12KDM4ECYP1A2
SCHEMBL1015781 0.79 DAO (0.47) DAOMAOAMAOBKDM4ECYP1A2
SCHEMBL30888553 0.77 FABP4 (0.43) CYP1A2CYP3A4MAPTCYP2C9CYP2C19
SCHEMBL3840252 0.74 MAOB (0.57) MAOAMAOBSLC22A12CYP1A2CYP3A4
SCHEMBL1017994 0.74 DAO (0.51) DAOMAOAMAOBKDM4ECYP1A2
SCHEMBL2475056 0.74 FFAR1 (0.52) SLC22A12TRPV4MRGPRX4
SCHEMBL20743670 0.73 MAOB (0.77) DAOMAOAMAOBKDM4EMAPT
SCHEMBL9550789 0.73 PRKAG1 (0.44) CYP3A4MAPTTP53SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10722599-B2 Lipid assemblies and uses thereof and some pH and electrostatic modulating lipids to be used in said assemblies YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2020-07-28 US disclosed
US-20180043036-A1 LIPID ASSEMBLIES AND USES THEREOF AND SOME pH AND ELECTROSTATIC MODULATING LIPIDS TO BE USED IN SAID ASSEMBLIES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2018-02-15 US disclosed
US-9152041-B2 Display panel including patterned spacer LG CHEM, LTD. (KR) 2015-10-06 US disclosed
EP-1779197-B1 DISPLAY PANEL INCLUDIDNG PATTERNED SPACER LG CHEMICAL LTD (KR) 2013-11-20 EP disclosed
EP-1289967-B1 TRIAZINE-BASED COMPOUND COMPRISING FUNCTIONALIZED ALKYLTHIO GROUPS, AND PHOTOPOLYMERIZATION INITIATOR LG CHEMICAL LTD (KR) 2009-10-28 EP disclosed
US-20080213514-A1 Obtained from a photosensitive resin composition comprising a 2,4-bis(trichloromethyl)-6-(p-substituted alkylthiophenyl) triazine photoiniator, an alkali-soluble photocurable binder, and a monomer such as dipentaerythritol hexaacrylate; high strength, sensitivity, residue characteristics, film uniformity LG CHEM, LTD. (KR) 2008-09-04 US disclosed
US-20080213353-A1 Liposomes encapsulate active agent; vehicles for the delivery of drugs and active agents as well as in the field of gene transfer; delayed, sustained or prolonged release, gradual release, timed release, pH dependent release YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2008-09-04 US disclosed
CN-1981238-A Display panel includidng patterned spacer LG CHEMICAL LTD (KR) 2007-06-13 CN disclosed
EP-1779197-A1 DISPLAY PANEL INCLUDIDNG PATTERNED SPACER LG Chem, Ltd. (KR) 2007-05-02 EP disclosed
WO-2006004364-A1 DISPLAY PANEL INCLUDIDNG PATTERNED SPACER LG CHEM, LTD. (KR) 2006-01-12 WO disclosed
US-6797739-B1 Triazene-based compound comprising functionalized alkylthio groups, and photopolymerization initiator LG CHEMICAL CO., LTD. (KR) 2004-09-28 US disclosed
EP-1289967-A1 TRIAZINE-BASED COMPOUND COMPRISING FUNCTIONALIZED ALKYLTHIO GROUPS, AND PHOTOPOLYMERIZATION INITIATOR LG Chemical Co. Ltd (KR) 2003-03-12 EP disclosed
WO-2001096317-A1 TRIAZINE-BASED COMPOUND COMPRISING FUNCTIONALIZED ALKYLTHIO GROUPS, AND PHOTOPOLYMERIZATION INITIATOR LG CHEMICAL CO., LTD (KR) 2001-12-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180043036-A1 LIPID ASSEMBLIES AND USES THEREOF AND SOME pH AND ELECTROSTATIC MODULATING LIPIDS TO BE USED IN SAID ASSEMBLIES PHOSPHO1, SGMS1, SGMS2 DAO 1914/4885MAOA 4274/4885MAOB 4713/4885
US-20080213353-A1 Liposomes encapsulate active agent; vehicles for the delivery of drugs and active agents as well as in the field of gene transfer; delayed, sustained or prolonged release, gradual release, timed release, pH dependent release LIPA, SLC47A1, CTSA DAO 3758/4885MAOA 1975/4885MAOB 3309/4885
US-10722599-B2 Lipid assemblies and uses thereof and some pH and electrostatic modulating lipids to be used in said assemblies PHOSPHO1, SGMS1, SGMS2 DAO 1914/4885MAOA 4274/4885MAOB 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.