Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4512128 | 0.99 | DRD2 (0.51) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL3834055 | 0.91 | MTNR1A (0.46) | DRD3MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL3837809 | 0.90 | KMT2A (0.47) | MEN1KMT2AMAPTGAAMTNR1A | |
| SCHEMBL3841806 | 0.90 | KMT2A (0.47) | MEN1KMT2AMAPTGAAMTNR1A | |
| SCHEMBL3837733 | 0.89 | MTNR1A (0.42) | DRD3MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL3838218 | 0.89 | CNR2 (0.44) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL3829260 | 0.89 | MTNR1A (0.43) | DRD3MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL3837724 | 0.89 | MTNR1A (0.43) | MEN1KMT2AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL3837761 | 0.86 | KDM4E (0.47) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL3878483 | 0.85 | KDM2B (0.46) | MTNR1AMTNR1BSMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931341-B1 | 1H-INDOLE-PYRIDINECARBOXAMIDE AND 1H-INDOLE-PIPERIDINECARBOXAMIDE DERIVATIVES AND THEIR USE AS TYROSINE HYDROXYLASE INDUCERS | SERVIER LAB (FR) | 2009-11-04 | — | — | EP | disclosed |