Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.42 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841806 | 0.99 | KMT2A (0.47) | MTNR1AMTNR1BKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3837809 | 0.99 | KMT2A (0.47) | MTNR1AMTNR1BKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3837761 | 0.95 | KDM4E (0.47) | MTNR1AMTNR1BKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3837724 | 0.94 | MTNR1A (0.43) | MTNR1AMTNR1BKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3829260 | 0.94 | MTNR1A (0.43) | MTNR1AMTNR1BKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3838218 | 0.94 | CNR2 (0.44) | MTNR1AMTNR1BKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3837733 | 0.92 | MTNR1A (0.42) | MTNR1AMTNR1BKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3844238 | 0.91 | DRD2 (0.52) | MTNR1AMTNR1BKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3841126 | 0.90 | CHRNB2 (0.45) | MTNR1AMTNR1BKMT2ALMNATSHR | |
| SCHEMBL3878483 | 0.90 | KDM2B (0.46) | MTNR1AMTNR1BLMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298813-A1 | USE OF NEUROPROTECTIVE COMPOUNDS IN OBTAINING MEDICAMENTS INTENDED FOR THE TREATMENT OF NEURODEGENERATING DISEASES | LES LABORATOIRES SERVIER (FR) | 2009-12-03 | — | — | US | disclosed |
| US-20090258883-A1 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds | LES LABORATOIRES SERVIER (FR) | 2009-10-15 | — | — | US | disclosed |
| EP-2101768-A2 | USE OF NEUROPROTECTIVE COMPOUNDS FOR OBTAINING DRUGS FOR TREATING NEURODEGENERATIVE DISEASES | Les Laboratoires Servier (FR) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008099083-A2 | USE OF NEUROPROTECTIVE COMPOUNDS FOR OBTAINING DRUGS FOR TREATING NEURODEGENERATIVE DISEASES | LES LABORATOIRES SERVIER (FR) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298813-A1 | USE OF NEUROPROTECTIVE COMPOUNDS IN OBTAINING MEDICAMENTS INTENDED FOR THE TREATMENT OF NEURODEGENERATING DISEASES | NLN, GAP43, SNCA | MTNR1A 70/4885MTNR1B 133/4885KMT2A 4227/4885 |
| US-20090258883-A1 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds | IDO1, AHR, IDO2 | MTNR1A 34/4885MTNR1B 70/4885KMT2A 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.