Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729262 | 0.80 | CREBBP (0.47) | ERCC1ERCC4CYP2C9CREBBPGRIN2D | |
| SCHEMBL15228262 | 0.80 | ERCC1 (0.44) | ERCC1ERCC4TSHRALDH1A1GLA | |
| SCHEMBL1921613 | 0.77 | KMT2A (0.54) | ERCC1ERCC4ALDH1A1LMNAHPGD | |
| SCHEMBL17546137 | 0.76 | ERCC1 (0.52) | ERCC1ERCC4TSHRALDH1A1LMNA | |
| SCHEMBL3843553 | 0.75 | ERCC1 (0.43) | ERCC1ERCC4TSHRALDH1A1HPGD | |
| SCHEMBL10816643 | 0.75 | ALDH1A1 (0.42) | ERCC1ERCC4TSHRALDH1A1LMNA | |
| SCHEMBL25420774 | 0.72 | EPHX2 (0.51) | ERCC1ERCC4TSHRALDH1A1GLA | |
| SCHEMBL4725368 | 0.71 | DYRK1A (0.60) | ERCC1ERCC4ALDH1A1GLAHPGD | |
| SCHEMBL3637120 | 0.70 | CSNK2A1 (0.46) | ERCC1ERCC4ALDH1A1GLAHPGD | |
| SCHEMBL2351513 | 0.68 | AURKA (0.45) | TSHRLMNAHPGDMAPTAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018193387-A1 | HETEROCYCLIC COMPOUNDS WITH MICROBIOCIDAL PROPERTIES | PI INDUSTRIES LTD. (IN) | 2018-10-25 | — | — | WO | disclosed |
| EP-2114898-A2 | NITROGEN-CONTAINING HETEROCYCLYL KETONES AND THEIR USE AS C-MET INHIBITORS | Amgen Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008103277-A2 | NITROGEN-CONTAINING HETEROCYCLYL KETONES AND THEIR USE AS C-MET INHIBITORS | AMGEN INC. (US) | 2008-08-28 | — | — | WO | disclosed |