Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PON1 | P27169 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHAT | P28329 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666881 | 0.98 | LMNA (0.41) | LMNATHRBL3MBTL1HPGDCYP3A4 | |
| Iodide SCHEMBL3820106 | 0.96 | LMNA (0.40) | LMNATHRBL3MBTL1HPGDCYP3A4 | |
| Bromide SCHEMBL20531184 | 0.96 | LMNA (0.40) | LMNATHRBL3MBTL1HPGDCYP3A4 | |
| SCHEMBL384827 | 0.90 | LMNA (0.38) | LMNATHRBL3MBTL1HPGDCYP3A4 | |
| Cyanate SCHEMBL665497 | 0.87 | LMNA (0.36) | LMNATHRBL3MBTL1HPGDCYP3A4 | |
| Phosphoric Acid SCHEMBL20531178 | 0.87 | LMNA (0.42) | LMNATHRBL3MBTL1HPGDCYP3A4 | |
| SCHEMBL12220256 | 0.87 | LMNA (0.33) | LMNATHRBL3MBTL1HPGDNPSR1 | |
| Acetic Acid SCHEMBL20531177 | 0.86 | LMNA (0.44) | LMNATHRBL3MBTL1HPGDNPSR1 | |
| Iodide SCHEMBL2535721 | 0.85 | LMNA (0.33) | LMNATHRBL3MBTL1HPGDNPSR1 | |
| SCHEMBL665507 | 0.84 | LMNA (0.35) | LMNATHRBL3MBTL1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110875435-B | Coating type organic electroluminescent device, display device and lighting device including the same | 乐金显示有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-110875435-A | Coating type organic electroluminescent device, display device and lighting device including the same | 乐金显示有限公司 | 2020-03-10 | — | — | CN | disclosed |
| EP-2997114-B1 | IONIC LIQUID COMPOSITION | RELIANCE INDUSTRIES LTD (IN) | 2018-10-17 | — | — | EP | disclosed |
| US-8101749-B2 | Process for the preparation of onium salts with a tetrafluoroborate anion having a reduced halide content | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-24 | — | — | US | disclosed |
| EP-1831179-B1 | METHOD FOR THE PRODUCTION OF ONIUM SALTS WITH TETRAFLUOROBORATE ANION HAVING A REDUCED HALIDE CONTENT | MERCK PATENT GMBH (DE) | 2010-11-03 | — | — | EP | disclosed |
| US-20090253912-A1 | PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH A TETRAFLUOROBORATE ANION HAVING A REDUCED HALIDE CONTENT | MERCK PATENT GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253912-A1 | PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH A TETRAFLUOROBORATE ANION HAVING A REDUCED HALIDE CONTENT | HCN4, PFAS, NUP205 | LMNA 2175/4885THRB 722/4885L3MBTL1 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.