Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.56 |
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTR3A | P46098 | 2/20 | 0.55 |
| ▸ | HTR1D | P28221 | 2/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | HTR3B | O95264 | 1/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607911 | 1.00 | ADRB2 (0.56) | ADRB2NCF1HTR2CALDH1A1HTR3A | |
| SCHEMBL1470389 | 0.87 | ADRB2 (0.56) | ADRB2NCF1HTR2CALDH1A1HTR3A | |
| SCHEMBL30511066 | 0.87 | ADRB2 (0.56) | ADRB2NCF1HTR2CALDH1A1HTR3A | |
| Hydrochloric Acid SCHEMBL31590331 | 0.85 | MAPT (0.56) | ADRB2NCF1HTR2CALDH1A1HTR3A | |
| SCHEMBL18308981 | 0.85 | HTR3A (0.48) | ADRB2NCF1HTR2CALDH1A1HTR3A | |
| SCHEMBL19403771 | 0.83 | ADRB2 (0.56) | ADRB2NCF1HTR2CALDH1A1HTR3A | |
| SCHEMBL8257492 | 0.83 | OPRD1 (0.43) | ADRB2NCF1ALDH1A1HTR3AHTR3E | |
| Hydrochloric Acid SCHEMBL19385636 | 0.82 | MAPT (0.56) | ADRB2NCF1HTR2CALDH1A1HTR3A | |
| SCHEMBL19385666 | 0.82 | ADRB2 (0.55) | ADRB2NCF1HTR2CALDH1A1HTR3A | |
| SCHEMBL3919469 | 0.82 | ADRB2 (0.55) | ADRB2NCF1HTR2CALDH1A1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409621-B | Targeted dopamine D 3 Diagnosis and treatment medicine for receptor and application thereof | 江苏省原子医学研究所 | 2023-09-08 | — | — | CN | disclosed |
| CN-114409621-A | Targeted dopamine D3Receptor diagnosis and treatment medicine and application thereof | 江苏省原子医学研究所 | 2022-04-29 | — | — | CN | disclosed |
| EP-2038268-B1 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET SOC CIV (FR) | 2015-11-04 | — | — | EP | disclosed |
| US-8802678-B2 | Carbonylated (aza) cyclohexanes as dopamine D3 receptor ligands | BIOPROJET (FR) | 2014-08-12 | — | — | US | disclosed |
| US-20090286801-A1 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2009-11-19 | — | — | US | disclosed |
| EP-2038268-A2 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007148208-A2 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286801-A1 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | DRD3, TACR2, TACR1 | ADRB2 56/4885NCF1 2774/4885HTR2C 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.