SCHEMBL3844786

SCHEMBL3844786

Cc1ccc(CC=Cc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.48
PPARG P37231 1/20 0.45
CYP1B1 Q16678 1/20 0.44
HTR2A P28223 3/20 0.44
IDO1 P14902 2/20 0.42
PAM P19021 1/20 0.42
MAPT P10636 4/20 0.42
LMNA P02545 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
EGFR P00533 1/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 2/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3847305 0.92 MAOB (0.54) MAOBPPARGCYP1B1MAPTLMNA
SCHEMBL6546952 0.90 NFE2L2 (0.46) IDO1MAPTRAB9AMEN1KMT2A
SCHEMBL28508047 0.90 NFE2L2 (0.46) IDO1MAPTRAB9AMEN1KMT2A
SCHEMBL1892917 0.85 MAOB (0.67) MAOBHTR2AIDO1PAMMAPT
SCHEMBL4256257 0.85 MAOB (0.67) MAOBHTR2AIDO1PAMMAPT
SCHEMBL163963 0.85 MAOB (0.67) MAOBHTR2AIDO1PAMMAPT
SCHEMBL6546781 0.84 TP53 (0.50) MAOBHTR2AIDO1PAMMAPT
SCHEMBL6546853 0.82 ALOX5 (0.47) MAOBIDO1MAPTLMNATDP1
SCHEMBL6546619 0.82 ALOX5 (0.47) MAOBIDO1MAPTLMNATDP1
SCHEMBL29288284 0.81 CYP19A1 (0.48) MAOBHTR2AIDO1PAMTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110396034-A A kind of preparation method of allyl compound SHANGHAI INST TECH 2019-11-01 CN disclosed
US-20180221298-A1 TRANSDERMAL DELIVERY SYSTEM EURO-CELTIQUE S.A. (LU) 2018-08-09 US disclosed
EP-2116527-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, METHOD FOR PRODUCTION OF THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM Corporation (JP) 2009-11-11 EP disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-20030129504-A1 Photosensitive resin compositon, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. 2003-07-10 US disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
US-5532292-A INORGANIC FIBERS ALCAN INTERNATIONAL LIMITED (CA) 1996-07-02 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0650507-A1 INTUMESCENT COMPOSITIONS. ALCAN INT LTD (CA) 1995-05-03 EP disclosed
WO-1994002545-A1 INTUMESCENT COMPOSITIONS ALCAN INTERNATIONAL LIMITED (CA) 1994-02-03 WO disclosed
EP-0341422-A2 Polymer mixture comprising a polyphenylene ether and a polyarylene sulphide GENERAL ELECTRIC COMPANY (US) 1989-11-15 EP disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed
US-4329529-A Traction fluids for traction drive transmissions NIPPON OIL CO., LTD. (JP) 1982-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180221298-A1 TRANSDERMAL DELIVERY SYSTEM HTR5A, MC1R, MCHR1 MAOB 480/4885PPARG 2938/4885CYP1B1 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.