SCHEMBL3844867

SCHEMBL3844867

Cc1cc(C)c2cnncc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
CYP2A6 P11509 1/20 0.46
ALDH1A1 P00352 3/20 0.35
PSMB5 P28074 3/20 0.35
MAPT P10636 3/20 0.35
KDM4E B2RXH2 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35
MPI P34949 1/20 0.35
KMT2A Q03164 1/20 0.35
GAA P10253 2/20 0.33
PARP1 P09874 1/20 0.33
LMNA P02545 1/20 0.33
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14599170 0.77 LMNA (0.37) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL18630341 0.77 ALDH1A1 (0.32) CYP1A2CYP2A6ALDH1A1CCR1CCR5
SCHEMBL14493595 0.77 CYP3A4 (0.39) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL30399331 0.77 NQO2 (0.36) ALDH1A1MAPTLMNA
SCHEMBL18630364 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL6844953 0.73 CYP1A2 (0.43) CYP1A2CYP2A6ALDH1A1PSMB5MAPT
SCHEMBL14493608 0.73 CYP11B1 (0.36) CYP2A6ALDH1A1KDM4ENOS3NOS1
SCHEMBL14599176 0.71 ALDH1A1 (0.34) CYP1A2ALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL3701838 0.71 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1PSMB5MAPT
SCHEMBL8404559 0.71 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US disclosed
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 US disclosed
US-9527828-B2 Method for expanding hematopoietic stem cells using heterocyclic compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-12-27 US disclosed
US-9527828-B2 Method for expanding hematopoietic stem cells using heterocyclic compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-12-27 US disclosed
EP-2218716-B1 METHOD FOR AMPLIFYING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND NISSAN CHEMICAL IND LTD (JP) 2016-11-16 EP disclosed
US-9328085-B2 Heterocyclic compounds and expansion agents for hematopoietic stem cells NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-03 US disclosed
US-9328085-B2 Heterocyclic compounds and expansion agents for hematopoietic stem cells NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-03 US disclosed
US-20140227780-A1 METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-08-14 US disclosed
US-20140227780-A1 METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-08-14 US disclosed
EP-2765187-A1 METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS Nissan Chemical Industries, Ltd. (JP) 2014-08-13 EP disclosed
EP-1079271-A1 Thermally processed image forming material FUJI PHOTO FILM CO., LTD. (JP) 2001-02-28 EP disclosed
US-6156491-A Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2000-12-05 US disclosed
US-6150084-A NUCLEATING AGENT AND DIPHOSPHORUS PENTOXIDE-DERIVED COMPOUND; ANTIFOGGING AGENT, CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 2000-11-21 US disclosed
EP-1045284-A1 Heat developing method for heat developable image recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-10-18 EP disclosed
EP-1041433-A1 Heat-developable photosensitive material and method for forming image using the same FUJI PHOTO FILM CO., LTD. (JP) 2000-10-04 EP disclosed
EP-1041435-A1 Heat-developable photographic material FUJI PHOTO FILM CO., LTD. (JP) 2000-10-04 EP disclosed
EP-1041434-A1 Heat-developable photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2000-10-04 EP disclosed
US-6100022-A COMPRISES A NONPHOTOSENSITIVE ORGANIC SILVER SALT, A PHOTOSENSITIVE SILVER HALIDE AND A POLYMERIC BINDER HAVING GLASS TRANSITION TEMPERATURE OF-30 TO 40 DEGREE C. ON A SUPPORT, AND IMAGE FORMING LAYER CONTAINING NUCLEATING AGENT FUJI PHOTO FILM CO., LTD. (JP) 2000-08-08 US disclosed
EP-1020760-A2 Heat developable image recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-07-19 EP disclosed
EP-0990946-A1 Heat-developable photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2000-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same OCIAD1, OXA1L, OCIAD2 CYP1A2 42/4885CYP2A6 923/4885ALDH1A1 229/4885
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME OCIAD1, OXA1L, CYP1A1 CYP1A2 42/4885CYP2A6 786/4885ALDH1A1 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.