SCHEMBL30399331

SCHEMBL30399331

Cc1cc(Br)cc2cnncc12

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 2/20 0.36
PRNP P04156 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
NOD2 Q9HC29 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14493573 0.77 CYP3A4 (0.35) NQO2PRNPNPSR1LMNAHPGD
SCHEMBL3844867 0.77 CYP1A2 (0.46) LMNAALDH1A1MAPT
SCHEMBL18630364 0.74 ALDH1A1 (0.32) ALDH1A1
SCHEMBL14493595 0.74 CYP3A4 (0.39) NQO2LMNAHPGDHTTALDH1A1
SCHEMBL6832989 0.74 MAOA (0.42) NQO2HTT
SCHEMBL27384772 0.72 LMNA (0.36) NQO2PRNPNPSR1LMNAHPGD
SCHEMBL558700 0.72 NOS3 (0.45) NQO2LMNAHTT
SCHEMBL30857895 0.72 LMNA (0.36) NQO2PRNPNPSR1LMNAHPGD
SCHEMBL2999406 0.70 NQO2 (0.37) NQO2LMNAHPGDALDH1A1
SCHEMBL14493608 0.69 CYP11B1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332173-A1 COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING REMIX THERAPEUTICS INC (US) 2025-10-30 US disclosed
EP-4416141-A1 COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING Remix Therapeutics Inc. (US) 2024-08-21 EP disclosed
WO-2023064880-A1 COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING REMIX THERAPEUTICS INC. (US) 2023-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332173-A1 COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING SNRPA, NSUN2, SNRPA1 NQO2 3129/4885PRNP 285/4885NPSR1 1883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.