Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864275 | 0.96 | MAOA (0.44) | HTR6HTR2CPPARGPPARAACHE | |
| SCHEMBL3840962 | 0.92 | HTR6 (0.54) | HTR6HTR2CPPARGPPARAACHE | |
| SCHEMBL3840597 | 0.87 | CYP4F2 (0.45) | PPARGPPARASLC22A12PPARDTBXAS1 | |
| SCHEMBL3841323 | 0.82 | TBXAS1 (0.49) | PPARGPPARAMAOAPPARDTBXAS1 | |
| SCHEMBL6361178 | 0.76 | HTR6 (0.46) | HTR6HTR2CACHE | |
| SCHEMBL5333496 | 0.73 | TBXAS1 (0.51) | PPARGPPARASLC22A12PPARDTBXAS1 | |
| SCHEMBL10414387 | 0.72 | HTR6 (0.80) | HTR6HTR2CMAOACYP1A2CYP2C19 | |
| SCHEMBL3381395 | 0.72 | CA12 (0.41) | PPARASLC22A12TBXAS1CYP1A2 | |
| SCHEMBL2439451 | 0.72 | PPARA (0.74) | PPARGPPARAACHEPPARD | |
| Hydrochloric Acid SCHEMBL4884079 | 0.71 | TBXAS1 (0.55) | PPARGPPARASLC22A12PPARDTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |