Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 9/20 | 0.37 |
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | CSF1R | P07333 | 3/20 | 0.37 |
| ▸ | LYN | P07948 | 3/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.37 |
| ▸ | SIK1 | P57059 | 3/20 | 0.37 |
| ▸ | SIK2 | Q9H0K1 | 3/20 | 0.37 |
| ▸ | SIK3 | Q9Y2K2 | 3/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848137 | 0.88 | FGFR1 (0.40) | ATMABL1CSF1RLYNTGFBR1 | |
| SCHEMBL3845007 | 0.83 | NPC1 (0.44) | PKMATMNPC1KDM4EHPGD | |
| SCHEMBL3846067 | 0.82 | SORT1 (0.39) | ATMNPC1HPGDALDH1A1POLB | |
| SCHEMBL3846919 | 0.80 | NPC1 (0.43) | PKMNPC1KDM4EHPGDTSHR | |
| SCHEMBL3846776 | 0.79 | ATM (0.41) | ATMHPGDALDH1A1HTT | |
| SCHEMBL3851820 | 0.76 | PIK3CD (0.40) | PKMTGFBR1NPC1KDM4EHPGD | |
| SCHEMBL3849232 | 0.75 | SIK1 (0.47) | PKMATMSIK1SIK2SIK3 | |
| SCHEMBL3848964 | 0.75 | CAMKK1 (0.39) | PKMNPC1KDM4EHPGDTSHR | |
| SCHEMBL3848140 | 0.73 | FGFR1 (0.33) | ATMABL1CSF1RLYNTGFBR1 | |
| SCHEMBL3845010 | 0.71 | NPC1 (0.37) | ATMABL1CSF1RLYNSIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048142-A2 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1382603-B1 | NITROGENOUS FUSED-RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | EISAI R&D MAN CO LTD (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |