SCHEMBL3845879

SCHEMBL3845879

CC=C(C)Oc1ccc(C23CC4CC(CC(C4)C2C2C4CC5CC(C4)CC2(c2ccc(OC(C)=CC)cc2OC(C)=CC)C5)C3)c(OC(C)=CC)c1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.32
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
XBP1 P17861 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3844883 0.82 GAA (0.37) EPHX2LMNATP53POLBGAA
SCHEMBL3845875 0.74 KMT2A (0.33) LMNATP53POLBMAPT
SCHEMBL3841450 0.71 ADRA2A (0.39) LMNAGAAMAPT
SCHEMBL3844863 0.68 GSTP1 (0.33)
SCHEMBL3845593 0.65 HSP90AA1 (0.39) POLBGAAMAPTXBP1
SCHEMBL10769497 0.64 LMNA (0.42) LMNATP53POLBGAAMAPT
SCHEMBL3844403 0.61 MEN1 (0.45) EPHX2LMNA
SCHEMBL3849676 0.60
SCHEMBL7474033 0.59 ELANE (0.42) LMNAGAAMAPT
SCHEMBL3841226 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed