Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27276534 | 0.74 | KMT2A (0.41) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1654189 | 0.73 | ATM (0.35) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9507537 | 0.71 | MEN1 (0.39) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL437417 | 0.67 | NPSR1 (0.41) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11871425 | 0.66 | MLYCD (0.37) | SMN1; SMN2ALDH1A1TSHRNPSR1MLYCD | |
| SCHEMBL28249141 | 0.66 | ALDH1A1 (0.40) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27787154 | 0.65 | ALDH1A1 (0.54) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1796482 | 0.65 | ALDH1A1 (0.41) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12913142 | 0.64 | PIN1 (0.45) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL200192 | 0.63 | ALDH1A1 (0.49) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799665-B1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | WILEX AG (DE) | 2009-08-19 | — | — | EP | disclosed |
| EP-1799665-A1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | Wilex AG (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006042678-A1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | WILEX AG (DE) | 2006-04-27 | — | — | WO | disclosed |