Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 11/20 | 0.61 |
| ▸ | TYMS | P04818 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATIC | P31939 | 2/20 | 0.53 |
| ▸ | GART | P22102 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768814 | 0.91 | DHFR (0.61) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL28344203 | 0.91 | DHFR (0.61) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL29003723 | 0.90 | DHFR (0.60) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL28105446 | 0.90 | DHFR (0.54) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL25167471 | 0.89 | DHFR (0.57) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL5427457 | 0.89 | DHFR (0.59) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL28273767 | 0.89 | DHFR (0.59) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL338037 | 0.88 | DHFR (0.57) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL1250396 | 0.88 | DHFR (0.62) | DHFRTYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL27942890 | 0.88 | DHFR (0.54) | DHFRTYMSKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7610074-B2 | Multi-functional plasmon-resonant contrast agents for optical coherence tomography | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-10-27 | — | — | US | disclosed |
| US-20050171433-A1 | Multi-functional plasmon-resonant contrast agents for optical coherence tomography | PURDUE RESEARCH FOUNDATION | 2005-08-04 | — | — | US | disclosed |