Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848529 | 0.87 | PTGS2 (0.30) | — | |
| SCHEMBL3855066 | 0.87 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3852642 | 0.86 | NPSR1 (0.32) | ALDH1A1 | |
| SCHEMBL3846760 | 0.84 | PDE7A (0.36) | ALDH1A1PDE7A | |
| SCHEMBL3850581 | 0.83 | AKT1 (0.33) | ALDH1A1 | |
| SCHEMBL3847469 | 0.81 | — | — | |
| SCHEMBL5852256 | 0.81 | ATM (0.32) | ALDH1A1 | |
| SCHEMBL3847835 | 0.76 | ALOX5AP (0.37) | ALDH1A1 | |
| SCHEMBL3846716 | 0.76 | POLB (0.33) | — | |
| SCHEMBL3846131 | 0.76 | MEN1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048142-A2 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1382603-B1 | NITROGENOUS FUSED-RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | EISAI R&D MAN CO LTD (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |