⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056866 | 0.76 | ANPEP (0.58) | — | |
| SCHEMBL1396820 | 0.72 | ENPEP (0.46) | — | |
| SCHEMBL3806259 | 0.71 | — | — | |
| SCHEMBL1694470 | 0.69 | — | — | |
| SCHEMBL28435468 | 0.69 | ANPEP (0.35) | — | |
| SCHEMBL3854505 | 0.68 | TYMS (0.55) | — | |
| SCHEMBL30900851 | 0.68 | ANPEP (0.44) | — | |
| Alcohol SCHEMBL628161 | 0.67 | TYMS (0.53) | — | |
| SCHEMBL27651573 | 0.67 | FDPS (0.36) | — | |
| SCHEMBL9181651 | 0.67 | TYMS (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160211-A1 | GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE, INC. (US) | 2010-06-24 | — | — | US | claimed |
| US-20040063916-A1 | Bactericides; antibiotics | CUMBERLAND PHARMACEUTICALS INC. | 2004-04-01 | — | — | US | claimed |
| JP-2004501161-A | — | — | 2004-01-15 | — | — | JP | claimed |
| US-20030207797-A1 | Glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups; and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful | CUMBERLAND PHARMACEUTICALS INC. | 2003-11-06 | — | — | US | claimed |
| EP-1292612-A2 | GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | Advanced Medicine, Inc. (US) | 2003-03-19 | — | — | EP | claimed |
| US-20020022590-A1 | Useful as antibiotics; reduced tissue accumulation and/or nephrotoxicity when administered to a mammal; useful against vancomycin-resistant microorganisms | CUMBERLAND PHARMACEUTICALS INC. | 2002-02-21 | — | — | US | claimed |
| WO-2001098328-A2 | GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE, INC. (US) | 2001-12-27 | — | — | WO | claimed |
| US-8859506-B2 | Glycopeptide phosphonate derivatives | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-20140024604-A1 | GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE, INC. (US) | 2014-01-23 | — | — | US | disclosed |
| US-8541375-B2 | Glycopeptide phosphonate derivatives | THERAVANCE, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20120283195-A1 | GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE, INC. (US) | 2012-11-08 | — | — | US | disclosed |
| US-8158580-B2 | Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin | THERAVANCE, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-8101575-B2 | Glycopeptide phosphonate derivatives | THERAVANCE, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| EP-1292612-A2 | GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | Advanced Medicine, Inc. (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1278549-A2 | CYCLODEXTRIN CONTAINING GLYCOPEPTIDE ANTIBIOTIC COMPOSITIONS | Advanced Medicine, Inc. (US) | 2003-01-29 | — | — | EP | disclosed |
| US-20020077280-A1 | Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin | CUMBERLAND PHARMACEUTICALS INC. | 2002-06-20 | — | — | US | disclosed |
| US-20020022590-A1 | Useful as antibiotics; reduced tissue accumulation and/or nephrotoxicity when administered to a mammal; useful against vancomycin-resistant microorganisms | CUMBERLAND PHARMACEUTICALS INC. | 2002-02-21 | — | — | US | disclosed |
| WO-2001098328-A2 | GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE, INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001082971-A2 | CYCLODEXTRIN CONTAINING GLYCOPEPTIDE ANTIBIOTIC COMPOSITIONS | THERAVANCE, INC. (US) | 2001-11-08 | — | — | WO | disclosed |
| EP-0647937-B1 | Binder for magnetic media | MINNESOTA MINING & MFG (US) | 1999-01-27 | — | — | EP | disclosed |