SCHEMBL384767

SCHEMBL384767

C=C[Si](C)(OC(=C)c1ccccc1)OC(=C)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.36
MAPT P10636 2/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
XBP1 P17861 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ELANE P08246 1/20 0.31
SRC P12931 1/20 0.31
CES1 P23141 1/20 0.31
F2 P00734 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11224354 0.79 TSHR (0.37) MAPTLMNAMEN1KMT2AXBP1
SCHEMBL6055084 0.79 TSHR (0.37) MAPTLMNAMEN1KMT2AXBP1
SCHEMBL347522 0.79 TSHR (0.37) MAPTLMNAMEN1KMT2AXBP1
SCHEMBL10912113 0.79 TSHR (0.48) AKT1MAPTLMNAMEN1KMT2A
SCHEMBL451686 0.74 TSHR (0.38) MAPTLMNAMEN1KMT2AXBP1
SCHEMBL388022 0.74 ESR1 (0.36) MAPTLMNAMEN1KMT2AXBP1
SCHEMBL14269384 0.73 TDP1 (0.36) MAPTLMNAMEN1KMT2AXBP1
SCHEMBL28392857 0.71 MAPT (0.41) MAPTLMNAMEN1KMT2AXBP1
SCHEMBL9038964 0.71 ALDH1A1 (0.40) MAPTLMNAMEN1KMT2AXBP1
SCHEMBL15525611 0.69 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101034-B2 Method for extending long-term electrical power cable performance NOVINIUM, INC. (US) 2012-01-24 US claimed
US-7976747-B2 Method for restoring power cables NOVINIUM, INC. (US) 2011-07-12 US claimed
US-7658808-B2 Dielectrics; polysiloxanes NOVINIUM, INC. (US) 2010-02-09 US claimed
US-20090176960-A1 METHOD FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE NOVINIUM, INC. (US) 2009-07-09 US claimed
US-20090133799-A1 METHOD FOR RESTORING POWER CABLES NOVINIUM, LLC 2009-05-28 US claimed
US-20080223498-A1 Method for extending long-term electrical power cable performance NOVINIUM, INC. (US) 2008-09-18 US claimed
US-8656586-B2 Method for treating electrical cable at sustained elevated pressure NOVINIUM, INC. (US) 2014-02-25 US disclosed
US-8205326-B2 Method for treating electrical cable at sustained elevated pressure NOVINIUM, INC. (US) 2012-06-26 US disclosed
US-20120102729-A1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM, INC. (US) 2012-05-03 US disclosed
US-8101034-B2 Method for extending long-term electrical power cable performance NOVINIUM, INC. (US) 2012-01-24 US disclosed
US-7976747-B2 Method for restoring power cables NOVINIUM, INC. (US) 2011-07-12 US disclosed
US-20100095521-A1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM, INC. (US) 2010-04-22 US disclosed
US-20090133799-A1 METHOD FOR RESTORING POWER CABLES NOVINIUM, LLC 2009-05-28 US disclosed
US-4764577-A Curable polymeric composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-08-16 US disclosed