SCHEMBL451686

SCHEMBL451686

C=C(O[Si](C)(OC)OC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
CES1 P23141 2/20 0.35
SRC P12931 1/20 0.35
MAPT P10636 4/20 0.33
LMNA P02545 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CES2 O00748 1/20 0.33
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
PAX8 Q06710 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6055084 0.90 TSHR (0.37) TSHRCES1SRCMAPTLMNA
SCHEMBL15525611 0.88 TSHR (0.31) TSHR
SCHEMBL347522 0.81 TSHR (0.37) TSHRCES1SRCMAPTLMNA
SCHEMBL11224354 0.81 TSHR (0.37) TSHRCES1SRCMAPTLMNA
SCHEMBL388022 0.76 ESR1 (0.36) TSHRCES1SRCMAPTLMNA
SCHEMBL384767 0.74 AKT1 (0.36) TSHRCES1SRCMAPTLMNA
SCHEMBL14269384 0.74 TDP1 (0.36) TSHRCES1SRCMAPTLMNA
SCHEMBL269069 0.73 TSHR (0.52) TSHRCES1SRCMAPTLMNA
SCHEMBL28392857 0.72 MAPT (0.41) TSHRMAPTLMNANPSR1MEN1
SCHEMBL9038964 0.72 ALDH1A1 (0.40) TSHRCES1MAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP claimed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
US-9944770-B2 Moisture curable compound with thiourea MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-17 US claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
EP-2614107-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2018-02-21 EP claimed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US claimed
US-9663621-B2 Moisture curable compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US claimed
US-9663657-B2 Moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US claimed
EP-2776162-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2014-09-17 EP claimed
WO-2013165552-A2 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC (US) 2013-11-07 WO claimed
WO-2013158236-A2 MOSITURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-10-24 WO claimed
WO-2013101751-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013101755-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013090132-A2 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
WO-2013090127-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
WO-2013071078-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-05-16 WO claimed
WO-2013070227-A1 MOISTURE CURABLE COMPOSITION OF A POLYMER HAVING SILYL GROUPS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-05-16 WO claimed
US-20120065308-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2012-03-15 US claimed