SCHEMBL347522

SCHEMBL347522

C=C(O[Si](C)(C)C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
MAPT P10636 2/20 0.36
LMNA P02545 2/20 0.36
ATM Q13315 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
XBP1 P17861 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 2/20 0.35
F2 P00734 1/20 0.34
CES1 P23141 3/20 0.34
SRC P12931 1/20 0.34
ELANE P08246 1/20 0.34
CES2 O00748 2/20 0.33
DAO P14920 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
TP53 P04637 1/20 0.33
EGFR P00533 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11224354 0.91 TSHR (0.37) TSHRMAPTLMNAATMMEN1
SCHEMBL6055084 0.86 TSHR (0.37) TSHRMAPTLMNAATMMEN1
SCHEMBL451686 0.81 TSHR (0.38) TSHRMAPTLMNAATMMEN1
SCHEMBL388022 0.81 ESR1 (0.36) TSHRMAPTLMNAATMMEN1
SCHEMBL8459393 0.81 HPGD (0.50) TSHRKMT2ASMN1; SMN2ALDH1A1CES1
SCHEMBL7230535 0.80 NAPRT (0.38) LMNAMEN1KMT2ASMN1; SMN2NPSR1
SCHEMBL19938127 0.80 ALDH1A1 (0.39) MAPTLMNAATMMEN1KMT2A
SCHEMBL10884057 0.79 CES2 (0.48) TSHRMAPTLMNAATMXBP1
SCHEMBL384767 0.79 AKT1 (0.36) TSHRMAPTLMNAATMMEN1
SCHEMBL14269384 0.79 TDP1 (0.36) TSHRMAPTLMNAATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118995044-A Silicon-rich anti-reflection coating resin, preparation method thereof and silicon-rich anti-reflection coating 宁波杭州湾新材料研究院 2024-11-22 CN claimed
CN-116284546-A Preparation method and preparation system of acrylic optical particles 安徽新涛光电科技有限公司 2023-06-23 CN claimed
US-20230100363-A1 MOLECULARLY IMPRINTED POLYMERS FOR EXTRACTION OF CANNABINOIDS AND USES THEREOF ORCA HOLDINGS, LLC 2023-03-30 US claimed
CN-115521529-A Composite material for preparing test tube cover and preparation method thereof 深圳市远景医疗器械模具有限公司 2022-12-27 CN claimed
CN-110526832-B Method for preparing polysubstituted alicyclic compound 浙江师范大学 2022-06-10 CN claimed
US-20220177666-A1 MOLECULARLY IMPRINTED POLYMERS FOR EXTRACTION OF CANNABINOIDS AND USES THEREOF ORCA HOLDINGS, LLC 2022-06-09 US claimed
CN-109134411-B Asymmetric 4H-pyran derivative and preparation method and application thereof 温州大学 2022-05-31 CN claimed
US-7678870-B2 Processable molecularly imprinted polymers THE JOHNS HOPKINS UNIVERSITY (US) 2010-03-16 US claimed
US-20070197746-A1 Processable molecularly imprinted polymers THE JOHNS HOPKINS UNIVERSITY 2007-08-23 US claimed
EP-1733211-A4 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS UNIV JOHNS HOPKINS (US) 2007-05-30 EP claimed
CN-1969181-A Processable molecularly imprinted polymers UNIV JOHNS HOPKINS (US) 2007-05-23 CN claimed
EP-1733211-A1 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS THE JOHNS-HOPKINS UNIVERSITY (US) 2006-12-20 EP claimed
WO-2005103655-A1 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS THE JOHNS HOPKINS UNIVERSITY (US) 2005-11-03 WO claimed
JP-62010036-A None JP disclosed
US-20250215256-A1 POLYMER FILM-FORMING COMPOSITION AND SELECTIVE POLYMER FILM-FORMING METHOD NISSAN CHEMICAL CORPORATION (JP) 2025-07-03 US disclosed
CN-119613408-A Bicyclic ketone compounds and methods of use thereof 豪夫迈·罗氏有限公司 2025-03-14 CN disclosed
US-4659862-A Process of preparing nitrodihydroaryl carbonyl compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-21 US disclosed
JP-S6210036-A PRODUCTION OF ALPHA-SUBSTITUTED KETONE AGENCY OF IND SCIENCE & TECHNOL 1987-01-19 JP disclosed
US-4448980-A BY CARBONYLATION WITH BIFLUORIDE CATALYSTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-15 US disclosed
US-4215044-A FLUORINATION OF AN UNSATURATED SILANOL COMPOUND WITH A PERHALOGENATED HYPOFLUORITE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230100363-A1 MOLECULARLY IMPRINTED POLYMERS FOR EXTRACTION OF CANNABINOIDS AND USES THEREOF CNR2, CNR1, CDIPT TSHR 4448/4885MAPT 299/4885LMNA 3698/4885
US-20220177666-A1 MOLECULARLY IMPRINTED POLYMERS FOR EXTRACTION OF CANNABINOIDS AND USES THEREOF CNR2, CNR1, CDIPT TSHR 4448/4885MAPT 299/4885LMNA 3698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.