SCHEMBL3847893

SCHEMBL3847893

Cc1c(C2=C(C3(C)Cc4ccccc4S3)C(F)(F)C(F)(F)C2(F)F)c2ccccc2n1C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.31
▸ POLB P06746 1/20 0.30
▸ HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28661847 0.72 GPR3 (0.39) LMNAPOLBHIF1A
SCHEMBL3847894 0.69 PLA2G10 (0.36) LMNAPOLBHIF1A
SCHEMBL3851303 0.67 POLB (0.34) POLBHIF1A
SCHEMBL9618083 0.67 — —
SCHEMBL3848599 0.65 EGFR (0.39) LMNAPOLBHIF1A
SCHEMBL3854145 0.65 HIF1A (0.36) LMNAPOLBHIF1A
SCHEMBL31098897 0.64 GSK3B (0.34) LMNAPOLB
SCHEMBL3851308 0.62 GSK3B (0.35) LMNAPOLBHIF1A
SCHEMBL9781277 0.60 — —
SCHEMBL29634190 0.59 KMT2A (0.54) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5222036-A — — None — — JP disclosed
EP-3732533-B1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL LTD (IE) 2025-12-10 — — EP disclosed
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
CN-111527442-A System and method for customizing photochromic articles 光学转变有限公司 2020-08-11 — — CN disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 — — US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
EP-1637570-B1 Color-memorizing photochromic writing instrument PILOT INK CO LTD (JP) 2007-06-27 — — EP disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
EP-1637570-A1 Color-memorizing photochromic writing instrument THE PILOT INK CO., LTD. (JP) 2006-03-22 — — EP disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 — — US disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
JP-H05222036-A SULFONATED DIARYLETHENE DERIVATIVE KANEBO LTD 1993-08-31 — — JP disclosed
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