Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.41 |
| ▸ | PPARD | Q03181 | 10/20 | 0.41 |
| ▸ | PPARG | P37231 | 12/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844320 | 0.90 | PPARA (0.40) | PPARAPPARDPPARG | |
| SCHEMBL3841422 | 0.90 | PKM (0.34) | PPARAPPARDPPARGLMNAHTT | |
| SCHEMBL3289571 | 0.90 | PPARA (0.39) | PPARAPPARDPPARGLMNAHTT | |
| SCHEMBL3844508 | 0.89 | PPARA (0.49) | PPARAPPARDPPARGSMN1; SMN2 | |
| SCHEMBL3842013 | 0.88 | PPARG (0.44) | PPARAPPARDPPARGLMNAHTT | |
| SCHEMBL3844532 | 0.88 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL3844301 | 0.86 | PPARG (0.39) | PPARAPPARDPPARG | |
| SCHEMBL3848920 | 0.86 | PPARG (0.43) | PPARAPPARDPPARGLMNAHTT | |
| SCHEMBL3845626 | 0.84 | PPARA (0.46) | PPARAPPARDPPARG | |
| SCHEMBL3846682 | 0.83 | PPARA (0.48) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |
| EP-1856065-A1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006092507-A1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2006-09-08 | — | — | WO | disclosed |