Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.39 |
| ▸ | PPARA | Q07869 | 15/20 | 0.38 |
| ▸ | PPARD | Q03181 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844320 | 0.91 | PPARA (0.40) | PPARGPPARAPPARD | |
| SCHEMBL3849202 | 0.90 | EPHX2 (0.34) | — | |
| SCHEMBL3284582 | 0.90 | PPARA (0.39) | PPARGPPARA | |
| SCHEMBL3844532 | 0.88 | PPARA (0.45) | PPARGPPARAPPARD | |
| SCHEMBL3841090 | 0.88 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL3848287 | 0.86 | PPARA (0.41) | PPARGPPARAPPARD | |
| SCHEMBL3842665 | 0.85 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL3844300 | 0.84 | PPARA (0.47) | PPARGPPARAPPARD | |
| SCHEMBL3287502 | 0.83 | PPARA (0.48) | PPARGPPARAPPARD | |
| SCHEMBL3843436 | 0.82 | PPARA (0.46) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |