Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840691 | 0.92 | SMPD1 (0.39) | LMNAHTTRAB9ASMN1; SMN2TSHR | |
| SCHEMBL3841459 | 0.91 | PKM (0.34) | PKMLMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL3843700 | 0.90 | SMPD1 (0.39) | LMNAHTTRAB9ASMN1; SMN2TSHR | |
| SCHEMBL3848287 | 0.90 | PPARA (0.41) | LMNAHTTRAB9ASMN1; SMN2PPARD | |
| SCHEMBL3849934 | 0.90 | PPARG (0.38) | HTTSMN1; SMN2MGAT2TSHRMAPK1 | |
| SCHEMBL3849202 | 0.87 | EPHX2 (0.34) | PKMEPHX2POLBL3MBTL1TSHR | |
| SCHEMBL3289571 | 0.85 | PPARA (0.39) | LMNAHTTRAB9ASMN1; SMN2MGAT2 | |
| SCHEMBL3847164 | 0.85 | PPARA (0.40) | LMNAHTTSMN1; SMN2PPARDPPARA | |
| SCHEMBL3842294 | 0.84 | PPARA (0.41) | LMNAHTTSMN1; SMN2L3MBTL1PPARD | |
| SCHEMBL3842107 | 0.84 | PPARG (0.38) | LMNAHTTSMN1; SMN2PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |