Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490022 | 1.00 | MAPT (0.50) | MAPTALDH1A1PKMHPGDALOX15 | |
| SCHEMBL4590265 | 0.85 | ALDH1A1 (0.44) | MAPTALDH1A1PKMHPGDALOX15 | |
| Pyridine SCHEMBL5081848 | 0.85 | HTT (0.46) | MAPTALDH1A1PKMHPGDALOX15 | |
| SCHEMBL2330083 | 0.83 | MAPT (0.50) | MAPTALDH1A1PKMHPGDALOX15 | |
| SCHEMBL31314863 | 0.83 | MAPT (0.50) | MAPTALDH1A1PKMHPGDALOX15 | |
| SCHEMBL11748785 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1PKMHPGDALOX15 | |
| SCHEMBL3851030 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1PKMHPGDALOX15 | |
| SCHEMBL9203850 | 0.79 | MAPT (0.47) | MAPTALDH1A1PKMHPGDALOX15 | |
| SCHEMBL577923 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1PKMHPGDALOX15 | |
| SCHEMBL22720204 | 0.79 | PIM1 (0.43) | MAPTALDH1A1PKMHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495619-B1 | ENHANCED STIFFNESS | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-12-17 | — | — | US | claimed |
| US-11332462-B2 | Heteroaryl compounds and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20200277286-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2020-09-03 | — | — | US | disclosed |
| WO-2019171088-A1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | NATIONAL HELLENIC RESEARCH FOUNDATION (GR) | 2019-09-12 | — | — | WO | disclosed |
| US-10189825-B2 | Heteroaryl compounds and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180118727-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2018-05-03 | — | — | US | disclosed |
| US-20150031709-A1 | Heteroaryl Compounds and Methods of Use Thereof | SUNOVION PHARMACEUTICALS, INC. (US) | 2015-01-29 | — | — | US | disclosed |
| US-20150031709-A1 | Heteroaryl Compounds and Methods of Use Thereof | SUNOVION PHARMACEUTICALS, INC. (US) | 2015-01-29 | — | — | US | disclosed |
| CN-103435857-A | Automobile tire tube rubber | SHANDONG YONGTAI CHEM GROUP CO | 2013-12-11 | — | — | CN | disclosed |
| WO-2013119895-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2013-08-15 | — | — | WO | disclosed |
| EP-1005565-A1 | NOVEL CAROTENOID-PRODUCING BACTERIAL SPECIES AND PROCESS FOR PRODUCTION OF CAROTENOIDS USING SAME | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-06-07 | — | — | EP | disclosed |
| US-5935808-A | CULTURING NOVEL BACTERIA CLASSIFIED AS GENUS PARACOCCUS IN NUTRIENT MEDIA CONTAINING SOURCES OF CARBON, NITROGEN AND INORGANIC SUBSTANCES, RECOVERING COMPOUNDS | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-08-10 | — | — | US | disclosed |
| WO-1999006586-A9 | NOVEL CAROTENOID-PRODUCING BACTERIAL SPECIES AND PROCESS FOR PRODUCTION OF CAROTENOIDS USING SAME | YISSUM RES DEV CO (IL) | 1999-04-29 | — | — | WO | disclosed |
| WO-1999006586-A1 | NOVEL CAROTENOID-PRODUCING BACTERIAL SPECIES AND PROCESS FOR PRODUCTION OF CAROTENOIDS USING SAME | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-02-11 | — | — | WO | disclosed |
| WO-1998012218-A1 | TRI- OR POLYSULPHIDE CONTAINING PEPTIDES HAVING IMMUNOMODULATING ACTIVITY | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-03-26 | — | — | WO | disclosed |
| EP-0454494-B1 | Calicheamicinone, derivatives and analogs thereof and methods of making the same | UNIV YALE (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0454494-A2 | Calicheamicinone, derivatives and analogs thereof and methods of making the same | YALE UNIVERSITY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031709-A1 | Heteroaryl Compounds and Methods of Use Thereof | COMT, GRIN2C, TPMT | MAPT 185/4885ALDH1A1 1165/4885PKM 1330/4885 |
| US-20200277286-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | COMT, GRIN2C, TPMT | MAPT 185/4885ALDH1A1 1165/4885PKM 1330/4885 |
| US-20180118727-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | COMT, GRIN2C, TPMT | MAPT 185/4885ALDH1A1 1165/4885PKM 1330/4885 |
| US-11332462-B2 | Heteroaryl compounds and methods of use thereof | COMT, GRIN2C, TPMT | MAPT 185/4885ALDH1A1 1165/4885PKM 1330/4885 |
| US-10189825-B2 | Heteroaryl compounds and methods of use thereof | COMT, GRIN2C, TPMT | MAPT 185/4885ALDH1A1 1165/4885PKM 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.