Pyridine

Pyridine

SCHEMBL5081848

O=C1c2ccccc2C(=O)N1SSN1C(=O)c2ccccc2C1=O.c1ccncc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.41
MAPT P10636 3/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
TP53 P04637 1/20 0.41
MAPK10 P53779 1/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 5/20 0.41
PKM P14618 2/20 0.41
KMT2A Q03164 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 2/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
MC4R P32245 1/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.40
CYP1A2 P05177 1/20 0.38
EHMT2 Q96KQ7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31490022 0.85 MAPT (0.50) HTTSMN1; SMN2MAPTNPC1RAB9A
SCHEMBL3848372 0.85 MAPT (0.50) HTTSMN1; SMN2MAPTNPC1RAB9A
Pyridine SCHEMBL28186854 0.78 CASP3 (0.61) HTTMAPTLMNAALDH1A1PKM
SCHEMBL4590265 0.72 ALDH1A1 (0.44) MAPTALDH1A1PKMKMT2AHSD17B10
Pyridine SCHEMBL29157767 0.72 TSHR (0.60) HTTSMN1; SMN2MAPTNPC1RAB9A
Pyridine SCHEMBL6552256 0.72 TSHR (0.60) HTTSMN1; SMN2MAPTNPC1RAB9A
SCHEMBL31314863 0.71 MAPT (0.50) HTTSMN1; SMN2MAPTNPC1RAB9A
SCHEMBL2330083 0.71 MAPT (0.50) HTTSMN1; SMN2MAPTNPC1RAB9A
Phthalic Anhydride SCHEMBL2379597 0.70 TDP1 (0.67) HTTSMN1; SMN2MAPTNPC1RAB9A
9,10-Phenanthrenequinone SCHEMBL7122347 0.70 PTPRC (0.62) HTTSMN1; SMN2MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008103728-A1 PRECURSOR COATINGS FOR SULFUR COATED CONTROLLED RELEASE FERTILIZERS HUDSON ALICE P (US) 2008-08-28 WO disclosed