Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848372 | 0.79 | MAPT (0.50) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL31490022 | 0.79 | MAPT (0.50) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL29016389 | 0.78 | ALDH1A1 (0.43) | PIM1ALDH1A1MAPTPKMHPGD | |
| SCHEMBL2330083 | 0.74 | MAPT (0.50) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL31314863 | 0.74 | MAPT (0.50) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL29845994 | 0.72 | DRD3 (0.45) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL919534 | 0.72 | DRD3 (0.45) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL30872008 | 0.71 | CASP3 (0.48) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL809458 | 0.71 | CASP3 (0.48) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL4590265 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTPKMHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204468-B | Asymmetric synthesis method of chiral alpha-thiocyano cyclic ketonic acid ester compound | 浙江工业大学 | 2021-02-02 | — | — | CN | claimed |
| US-12545651-B2 | Diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2026-02-10 | — | — | US | disclosed |
| CN-116535341-B | Method for synthesizing alpha-thiocyano-beta-dicarbonyl compounds by utilizing photocatalytic oxidation strategy | 新乡医学院 | 2025-01-28 | — | — | CN | disclosed |
| CN-115894329-A | Synthesis method of axial chiral indole derivative containing 2-thiocyano-3-aryl | 泽升科技(广州)有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114835625-A | Synthesis method of axial chiral indole derivative containing 2-thiocyano-3-aryl | 泽升科技(广州)有限公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20220227719-A1 | A diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2022-07-21 | — | — | US | disclosed |
| CN-110229114-B | Remove C2-toSymmetric diphenylamine type chiral bisoxazoline ligand and synthetic method and application thereof | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-110204468-B | Asymmetric synthesis method of chiral alpha-thiocyano cyclic ketonic acid ester compound | 浙江工业大学 | 2021-02-02 | — | — | CN | disclosed |
| CN-110204468-B | Asymmetric synthesis method of chiral alpha-thiocyano cyclic ketonic acid ester compound | 浙江工业大学 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020238559-A1 | DE-C2-SYMMETRIC DIPHENYLAMINE-TYPE CHIRAL BISOXAZOLINE LIGAND, SYNTHESIS METHOD THEREFOR AND USE THEREOF | 浙江工业大学 | 2020-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227719-A1 | A diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | AOC1, AOC2, AOC3 | PIM1 4803/4885ALDH1A1 197/4885MAPT 3073/4885 |
| US-12545651-B2 | Diphenylamine-linked chiral bis(oxazoline) ligand without C2-symmetry, synthesis method and application thereof | AOC2, AOC1, AOC3 | PIM1 4185/4885ALDH1A1 318/4885MAPT 3032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.